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Diabetes Device Guide — Juicebox Podcast
Juicebox Podcast · Diabetes Technology

Diabetes Device Guide

Every major insulin pump, CGM, DIY system, and smart pen — explained in plain language, grounded in clinical evidence, and connected to the Juicebox episode that covers it best.

14 Device Profiles Three Knowledge Tiers Each Clinical Evidence Cited Built for Patients & Clinicians Updated 2025–2026

Device specifications change frequently — always verify current information directly with the manufacturer before making any decisions. Full disclaimer.

About This Guide

One place for every device, explained three ways.

Every profile has three tiers: Just Starting Out (what it is and why it matters), Getting the Most from It (settings, practical use, real-world tips), and Deep Dive (algorithm architecture, clinical evidence, full prescribing reference). Use whichever tier fits where you are. Built from Juicebox Podcast episodes and updated regularly as devices evolve.

14Device Profiles
3Tiers Per Device
39Algorithm Pumping Episodes
2026Current as of
🎙️
Juicebox Podcast Series Algorithm Pumping — 39 Episodes

Loop, iAPS, Omnipod 5, Medtronic 780G, Control-IQ, real users, real outcomes. The audio companion to this guide. juiceboxpodcast.com → Series → Algorithm Pumping

Listen Now →
⚡

Automated Insulin Delivery (AID)

5 profiles
💊
AID · Tubeless Juicebox Sponsor
Omnipod 5
The tubeless AID — SmartAdjust algorithm, Dexcom G6/G7 or Libre, pharmacy access, ages 2+. 69,902 real-world users.
Read Profile →
🩺
AID · Tubed Juicebox Sponsor
Tandem Mobi & t:slim X2
Control-IQ+ with AutoBolus, Sleep Activity, the world's smallest tubed pump (Mobi), and remote software updates. Ages 2+.
Read Profile →
🎯
AID · Tubed
MiniMed 780G
The lowest commercial AID target (100 mg/dL). SmartGuard auto-corrections every 5 min, Meal Detection, and three CGM options. Real-world TIR 73–79%.
Read Profile →
🤖
AID · Bionic
iLet Bionic Pancreas
Just tell it your weight. No carb ratios, no ISF, no basal rates to set. NEJM 2022 pivotal: +11% TIR, −0.5% A1c. Meal announcement by size only.
Read Profile →
🔊
AID · Tubeless
twiist
Tidepool Loop algorithm (FDA-cleared), acoustic dosing confirmation, meal presets, pharmacy access. Dean Kamen origin. $0 to start, ~$50/month refill.
Read Profile →
💊

Manual Insulin Pumps

1 profile
🏪
Manual · Tubeless Juicebox Sponsor
Omnipod Dash
The only full-featured pump available at the pharmacy. No CGM required, no c-peptide needed. The primary hardware for DIY Loop and Trio. Under $50/month average copay.
Read Profile →
📡

Continuous Glucose Monitors (CGM)

4 profiles
📊
CGM · 10/15 Day Juicebox Sponsor
Dexcom G6, G7 & Stelo
The leader in AID compatibility — works with every commercial system plus DIY. G7 MARD 8.2%. Stelo for non-insulin users. Jake Leach interview: jbp954.
Read Profile →
🔵
CGM · 15 Day
FreeStyle Libre 2 Plus & 3 Plus
World's smallest CGM (3 Plus). Libre 2 and 3 discontinued Sept 2025 — Plus versions are current. Universal Libre app (April 2025). US Med distributes nationwide.
Read Profile →
🔬
Implantable · 180/365 Day
Eversense E3 & 365
The only implantable CGM. E3 lasts 180 days; 365 lasts one full year — one insertion, one year of data. No adhesive, no warmup after insertion. twiist-compatible.
Read Profile →
🛡️
CGM · 6–15 Day
Medtronic / MiniMed CGMs
Guardian 4, Simplera Sync, and the Abbott-powered Instinct (15-day). Required for MiniMed 780G SmartGuard. Also pairs with InPen for real-time Smart MDI.
Read Profile →
🔧

DIY & Open-Source AID

3 profiles
🔄
DIY · Not FDA-Cleared
DIY Loop Overview
The community-built AID ecosystem that preceded every commercial system. Loop, iAPS, Trio, AndroidAPS — what they are, how they compare, and 39 Juicebox episodes covering them.
Read Profile →
⚡
iOS · oref1 · Not FDA-Cleared
Trio
The most advanced iOS open-source AID — SMBs, Unannounced Meals, Dynamic ISF, Autotune. OpenAPS → iAPS → Trio lineage. This is what Arden uses.
Read Profile →
🤖
Android · oref1 · Not FDA-Cleared
AndroidAPS
Trio for Android — same oref1 algorithm, broadest pump compatibility (DANA, Accuchek, Omnipod, more), remote bolusing via AAPSClient, smartwatch support. v3.3.2.1.
Read Profile →
✏️

Smart Insulin Pens

1 profile
💡
MDI · Smart Pen
InPen Smart Insulin Pen
Dose logging, bolus calculator, IOB tracking, Missed Meal Detection (FDA Nov 2024), temperature alerts. ADA 2025 Grade B recommendation. ~$60 with insurance. For MDI patients.
Read Profile →
⚠️ This guide is for educational purposes only and does not constitute medical advice. Device capabilities, compatibility, and clinical recommendations change frequently. Always consult your healthcare provider before making changes to your diabetes management. Full disclaimer.

Juicebox Podcast · juiceboxpodcast.com · Device Guide compiled from manufacturer documentation, clinical literature, PANTHER resources, and Juicebox episode content.

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