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Tandem Mobi & t:slim X2 — Device Guide | Juicebox Podcast
Device Guide · Automated Insulin Delivery

Tandem Mobi & t:slim X2

Two very different pumps. One algorithm. Both run Control-IQ+ — the only AID system with an 8-hour extended bolus during automation, a dedicated Sleep Activity mode, and AutoBolus for missed meals.

🔄 Control-IQ+ Launched March 2025 · Free Update for In-Warranty Customers

Device specifications change frequently — always verify current information directly with the manufacturer before making any decisions. Full disclaimer.

Juicebox Podcast · Tandem Diabetes Care · Clinical Literature · PANTHER Program

New to Tandem? Start here.

Same Algorithm, Different Hardware

Control-IQ+ — One Algorithm, Two Pumps

Tandem makes two pumps — the t:slim X2 and the Mobi — and both run the same Control-IQ+ algorithm. The algorithm is where the clinical work happens: a 30-minute glucose prediction engine that adjusts basal every 5 minutes, delivers automated correction boluses, and has unique modes for sleep and exercise. The choice between pumps is about hardware fit, not performance.

🎙️

Tandem Diabetes Care is a current Juicebox Podcast sponsor. The Algorithm Pumping series covers Control-IQ in real-world use: Episode #1171 — Pump & CGM Overview Part 2 · Full series at juiceboxpodcast.com → Series → Algorithm Pumping

Choose Your Pump
Smallest tubed AID No screen iPhone controlled Waterproof IP28 Wireless charging 200-unit reservoir 5" tubing option Apple Watch bolus
📱

Controlled by iPhone

The Mobi has no screen. All settings, boluses, and status are managed through the Tandem t:slim mobile app on a compatible iPhone (iOS). An Android app received FDA approval and is launching in 2026. There is one physical button on the pump for bolusing if your phone isn't handy.

🤏

Smallest Tubed AID Available

The Mobi fits in a coin pocket. It can be worn on the body with an adhesive sleeve (sold separately), clipped to clothing, or slipped into a pocket. The 5-inch tubing option — exclusive to Mobi — minimizes the tubing between pump and infusion site.

🌊

Waterproof

Rated IP28 — tested at 8 feet for 2 hours. You can swim with the Mobi. The t:slim X2 is not waterproof (watertight only — no swimming or hot tubs). For patients who are active in water, Mobi is the only Tandem option.

⌚

Apple Watch Bolus

When paired with the standard Dexcom G7 (10-day), you can view glucose data and deliver boluses directly from Apple Watch — without picking up your phone. Not available with G6.

⚠️

CGM limitation: Mobi works with Dexcom G6 and standard Dexcom G7 (10-day) only. It does not support FreeStyle Libre 3 Plus. If your patient uses or prefers Libre, the t:slim X2 is the correct pump.

Color touchscreen 300-unit reservoir Dexcom G6/G7 + Libre 3 Plus iOS + Android Bolus on pump or phone ~5-day battery Not waterproof
📺

Color Touchscreen

The t:slim X2 has a full color touchscreen on the pump itself — you can bolus, check status, and adjust settings directly on the device without a phone. The app (iOS + Android) provides additional control and data viewing.

💉

300-Unit Reservoir

50% more reservoir capacity than the Mobi's 200 units. Meaningful for patients with higher insulin requirements. Both pumps use 3-day infusion set changes.

📡

Widest CGM Compatibility

Works with Dexcom G6, Dexcom G7, and FreeStyle Libre 3 Plus (early access rolled out late 2025). The only Tandem pump compatible with Libre — and the only AID system except twiist to support both Dexcom and Libre in the U.S.

🔌

Rechargeable Battery

Rechargeable via USB — approximately 5 days per charge. Charges quickly. Uses a standard cable. Note: the t:slim X2 is watertight (IPX7, 3 feet, 30 minutes) but not waterproof — no swimming or hot tub use.

Shared Algorithm · Both Pumps

What Control-IQ+ Does — Regardless of Which Pump You Use

🔮

30-Minute Prediction

Control-IQ+ looks 30 minutes ahead using CGM data. If glucose is predicted above 160 mg/dL, basal increases. If predicted above 180 mg/dL, an AutoBolus fires. If trending low, basal decreases or suspends.

💊

AutoBolus

If glucose is predicted to rise above 180 mg/dL, the algorithm calculates a correction bolus targeting 110 mg/dL and delivers 60% of it — automatically, up to once per hour. This covers missed or underestimated meal boluses.

🌙

Sleep Activity Mode

The only AID system with a dedicated Sleep Activity setting. At night it targets 112.5–120 mg/dL — more aggressive than the default day target. Real-world data shows 90% overnight TIR with Sleep Activity active.

🏃

Exercise Activity Mode

Raises the treatment target to 140–160 mg/dL to reduce hypoglycemia risk during activity. Set before exercise, return to default after. Available on both pumps.

For Clinicians · Quick Reference

Choosing Between Mobi and t:slim X2

Choose Mobi When

Patient wants the smallest possible pump. Active in water (swimming). Comfortable with phone-only control. Uses Dexcom G6 or G7. Wants Apple Watch bolus capability. Android users — note Android app launching 2026.

Choose t:slim X2 When

Patient prefers on-pump screen control. Higher insulin needs (300-unit reservoir). Uses or prefers FreeStyle Libre 3 Plus. Uses Android now. Patient not comfortable relying on phone for all pump functions.

Both Pumps Share

Control-IQ+ algorithm. AutoBolus. Sleep Activity (90% overnight TIR). Exercise Activity. 8-hour extended bolus in automation. Temp Basal 0–250% in automation. 3-day infusion set changes. 4-year warranty. Tandem Source data platform.

Free Algorithm Updates

Control-IQ+ launched March 2025 as a free remote software update for all eligible in-warranty Tandem customers. This means patients on older Control-IQ hardware can access the new algorithm without buying new hardware — verify eligibility at tandemdiabetes.com.

📋
PANTHER Program — Full AID Device Comparison Chart C|A|R|E|S Framework · Barbara Davis Center · pantherprogram.org

Sources

juiceboxpodcast.com — Episode #1171: Pump & CGM Overview Part 2 (Control-IQ, Mobi) tandemdiabetes.com — Tandem Mobi Product Page tandemdiabetes.com — Control-IQ+ Technology DiaTribe — Tandem Control-IQ+: How It Works, Features, Latest Updates tandemdiabetes.com — Control-IQ+ U.S. Launch Announcement (March 2025)
Getting the Most from It

Control-IQ+ Features — What Changes Everything

Control-IQ+ introduced three features that no other AID system has: an 8-hour extended bolus during automation, a Temp Basal rate while automation is active, and a dedicated Sleep Activity mode with real-world 90% overnight TIR data. Here's how to use each one.

The New Features in Control-IQ+
Control-IQ+ is the only AID system that allows an extended bolus while automation remains active. You can split a meal bolus over up to 8 hours — typically giving about 60% immediately and spreading the rest over several hours. This is designed for high-fat, high-protein meals (pizza, Thanksgiving dinner, fatty takeout) that cause delayed glucose rises. The algorithm continues making automated adjustments simultaneously. Other AID systems either don't offer extended bolus at all, or require you to turn off automation to use it. Important: if you swap an insulin cartridge mid-extended-bolus, it cancels. Complete cartridge changes before starting or plan around them.
Previously, activating a Temp Basal required turning off Control-IQ. Now you can set a temporary basal rate from 0–250% for up to 72 hours while automation stays on. This is useful for situations like illness (increase), prolonged exercise (decrease), or unusual insulin resistance patterns. The algorithm works within the Temp Basal ceiling you set — so if you set 150%, the algorithm can still decrease or suspend below that as needed. Temp Basal returns to normal automatically when the time expires.
Sleep Activity targets a narrower, lower range: 112.5–120 mg/dL. The algorithm is more aggressive overnight — proactively delivering insulin to hold glucose in this tighter range rather than the daytime target of 112.5–160 mg/dL. Real-world data shows users who activate Sleep Activity consistently achieve ~90% overnight TIR. The key for most users is actually turning it on — it doesn't activate automatically. The most common mistake is not using it because setup feels optional. For most users, Sleep Activity significantly changes the overnight experience.
When CGM data predicts glucose will rise above 180 mg/dL, Control-IQ+ automatically calculates a correction bolus targeting 110 mg/dL and delivers 60% of that amount. This happens up to once per hour. If you forget to bolus for a meal entirely and glucose starts rising, AutoBolus begins firing corrections. It won't perfectly match a proper meal bolus, but it significantly reduces post-meal excursions from missed doses. This feature is one reason Control-IQ+ can improve outcomes even for people who occasionally miss meal boluses.
Tandem pumps can receive software updates remotely — without mailing in or replacing the device. Control-IQ+ rolled out as a free update to all eligible in-warranty Tandem customers in March 2025. This means patients who bought a t:slim X2 or Mobi before the algorithm launched now have access to the new features. In clinical practice, this means asking current Tandem patients whether they've updated — many haven't, and the improvement in features is significant. The update is done through the Tandem Source app.
Side-by-Side

Mobi vs t:slim X2 — Key Differences

FeatureTandem Mobit:slim X2
ScreenNone — phone onlyColor touchscreen
Reservoir200 units300 units
WaterproofYes — IP28 (8 ft, 2 hrs)No (watertight only)
CGM supportDexcom G6/G7 onlyDexcom G6/G7 + Libre 3 Plus
Android app2026Available now
Wireless chargingYesNo (USB cable)
Tubing option5" or standardStandard only
Apple Watch bolusYes (with G7)No
SizeCoin-pocket smallTraditional pump size
Wear optionsPocket / clip / sleeve / on-bodyPocket / clip
AlgorithmControl-IQ+ — identical on both
For Clinicians · Settings & Optimization

What to Review at Every Tandem Follow-Up

Is Sleep Activity On?

The most common missed optimization. Patients often don't realize it doesn't activate automatically. Confirm it's enabled and scheduled for sleep hours. Real-world data: 90% overnight TIR with Sleep Activity — compared to ~70% overall TIR in the pivotal trial.

Have They Updated?

Confirm patient is running Control-IQ+ (not the original Control-IQ). Key new features they may be missing: Extended Bolus up to 8 hours, Temp Basal during automation, expanded age/weight indications. Update via Tandem Source app.

Extended Bolus Education

Many patients don't know about the 8-hour extended bolus or don't understand when to use it. Counsel specifically for high-fat, high-protein meals. Common use cases: pizza, Chinese takeout, restaurant meals, holiday dinners.

Tandem Source Data

Pull reports via Tandem Source (clinic platform). Review: TIR breakdown, Sleep Activity TIR vs daytime TIR, AutoBolus frequency (high AutoBolus = patient often missing meal boluses), Temp Basal usage.

📋
PANTHER Program — t:slim X2 / Control-IQ C|A|R|E|S One-Sheet (PDF) Full clinical reference · Barbara Davis Center · pantherprogram.org

Sources

juiceboxpodcast.com — Episode #1171: Pump & CGM Overview (Control-IQ, Mobi) tandemdiabetes.com — Control-IQ+ Technology Overview DiabeTech — Tandem's Control-IQ+ Upgrade: What You Should Know DiaTribe — Tandem t:slim X2: How It Works, Features, Latest Updates pantherprogram.org — t:slim X2 / Control-IQ C|A|R|E|S One-Sheet (PDF) ADCES / danatech — Tandem Mobi Clinical Reference
Deep Dive

The Algorithm, the Evidence & the Full Clinical Picture

Control-IQ has one of the deepest published evidence bases of any AID algorithm — pivotal trial data, real-world studies, and the first NEJM-published AID trial in type 2 diabetes. Here's what the science actually says.

Clinical Evidence

What the Studies Show

70% TIR — Pivotal Trial vs. 59% standard care — +2.6 hrs/day (Buckingham et al., NEJM 2021)
0.3% A1C Reduction vs. standard care in pivotal trial — 156 vs 170 mg/dL avg glucose
74% TIR Real-World Average TIR at 12 months — 9,000 real-world users (Beck et al., 2023)
>10% TIR Gain in 2 Weeks Real-world study: TIR increased within 14 days of starting Control-IQ
90% Overnight TIR Real-world data with Sleep Activity mode active
+24% TIR in T2D 48%→64% — Control-IQ+ T2D NEJM study (Kudva et al., 2025)

The benefits of AID are proven — better sleep, fewer adverse events, better glucose control. Any one of these outcomes can be life-changing for children living with diabetes and their families.

— Dr. Paul Wadwa, Director, Pediatric Clinic, Barbara Davis Center for Diabetes · University of Colorado · via Tandem Control-IQ+ Launch Press Release (March 2025)
A study published in the New England Journal of Medicine in March 2025 (Kudva et al.) examined Control-IQ+ in adults with insulin-requiring type 2 diabetes. At 13 weeks: TIR increased from 48% to 64% (+24%), and A1C dropped from 8.2% to 7.3% (-0.9%). This represented one of the largest TIR improvements ever seen in a T2D AID trial. Control-IQ+ with the t:slim X2 is FDA-approved for adults 18+ with type 2 diabetes — a significant expansion from the type 1-only indication of earlier Control-IQ.
Control-IQ+ builds a continuous glucose forecast using current CGM data and known insulin on board. Every 5 minutes it evaluates: Is glucose predicted to be above 160 mg/dL in 30 minutes? If yes → increase basal. Is it predicted above 180? If yes → calculate and deliver 60% of a correction bolus targeting 110 mg/dL (AutoBolus, up to once/hour). Is it predicted to fall below 70? If yes → decrease or suspend basal. This forward-looking model means the system acts before glucose excursions happen rather than reacting after — the core advantage over older predictive low glucose suspend systems.
Every other commercially available AID system requires you to turn off automation to use an extended bolus. Control-IQ+ is unique in allowing up to an 8-hour extended bolus while the algorithm remains active. Clinically this matters for high-fat, high-protein meals where glucose rises are delayed by 2–6 hours after eating. A typical pizza meal might require insulin spread over 4–5 hours. With other systems, using an extended bolus means the algorithm can't respond to what's happening. With Control-IQ+, both strategies run simultaneously — extended delivery plus real-time adjustments based on what the CGM is actually seeing.
Tandem announced Libre 3 Plus compatibility with the t:slim X2 in June 2025. Rollout began in an early access program in late 2025, with broader access expected to continue through 2026. The Mobi does not and is not planned to support Libre. One limitation: when the t:slim X2 is connected to Libre 3 Plus, there is currently no remote follow feature for caregivers — Libre 3 Plus can only connect to one system at a time. Parents of young children may prefer Dexcom specifically because caregiver follow remains available simultaneously.
Tandem has confirmed development of a tubeless Mobi platform — a patch pump version of the Mobi expected to maintain the Control-IQ+ algorithm. Timeline not yet confirmed. Additionally, Tandem announced in June 2025 that future versions of its AID systems will integrate a new Abbott sensor designed to monitor both glucose and ketones simultaneously — potentially enabling real-time DKA risk monitoring within the AID system. Both remain in development; verify current status at tandemdiabetes.com.
For Clinicians & Educators · Full C|A|R|E|S Reference

Tandem Control-IQ+ — Complete Clinical Breakdown

The C|A|R|E|S Framework from the PANTHER Program. Applies to both t:slim X2 and Tandem Mobi — hardware differences noted where relevant.

C
Calculates

30-min predictive algorithm. Adjusts basal every 5 min. AutoBolus: 60% of calculated correction, target 110 mg/dL, up to 1×/hour when predicted >180 mg/dL. Sleep Activity: targets 112.5–120 mg/dL. Exercise Activity: targets 140–160 mg/dL. Increases basal when predicted >160 mg/dL.

A
Adjustable

Basal rates, I:C ratio, ISF, Active Insulin Time all programmed by user. NEW in Control-IQ+: Temp Basal 0–250% up to 72 hrs during automation; Extended Bolus up to 8 hours during automation (only AID system). Activity modes: Sleep / Exercise. Cannot adjust correction target (fixed at 110 mg/dL for AutoBolus).

R
Reverts

Automation can be turned off manually; pump operates with basal rates and standard bolus calculator. CGM signal loss pauses automated adjustments — pump continues basal. If cartridge swapped mid-extended-bolus, extended bolus cancels. Activity modes must be set manually — Sleep does not auto-activate at bedtime.

E
Education

Always bolus for meals — AutoBolus supplements but doesn't replace meal boluses. Enable Sleep Activity every night for best overnight TIR. Use Extended Bolus for high-fat/protein meals. Temp Basal for exercise/illness. Cartridge changes: complete before starting extended bolus. Confirm software update to Control-IQ+ (free).

S
Sensor / Sharing

Mobi: Dexcom G6, standard G7 (10-day) only. t:slim X2: Dexcom G6, G7, FreeStyle Libre 3 Plus (rolling). Caregiver follow: Available via Dexcom Follow; Libre 3 Plus on t:slim limits caregiver sharing simultaneously. Data: Tandem Source platform (clinic + patient). Apple Watch bolus: Mobi + standard G7 only.

📊 Clinical Evidence Summary

Pivotal trial (Buckingham et al.): TIR 70% vs 59% (+2.6 hrs/day), A1C −0.3%. Real-world (Beck et al., 2023): 9,000 users, TIR >10% increase within 2 weeks, 74% TIR at 12 months. Sleep Activity: 90% overnight TIR (real-world). T2D (Kudva et al., NEJM 2025): TIR +24% (48%→64%), A1C −0.9% at 13 weeks.

Source: PANTHER Program · Barbara Davis Center · University of Colorado · Tandem Diabetes Care product documentation · Published clinical literature

📋
PANTHER Program — t:slim X2 / Control-IQ C|A|R|E|S One-Sheet (PDF) Printable clinical reference · pantherprogram.org
📊
Full AID Device Comparison — All Systems MiniMed 780G · iLet · t:slim X2 · Omnipod 5 · twiist · pantherprogram.org

Sources

juiceboxpodcast.com — Episode #1171: Pump & CGM Overview Part 2 (Control-IQ, Mobi) tandemdiabetes.com — Control-IQ+ Technology tandemdiabetes.com — Tandem Mobi Product Page tandemdiabetes.com — Control-IQ+ U.S. Launch (March 18, 2025) DiaTribe — Tandem Control-IQ+: How It Works, Features, Latest Updates DiaTribe — Tandem t:slim X2: How It Works, Features, Latest Updates DiabeTech — Tandem Control-IQ+ Upgrade: What You Should Know DiabetesWise — t:slim X2 vs Tandem Mobi Device Comparison ADCES / danatech — Tandem Mobi Clinical Reference pantherprogram.org — t:slim X2 / Control-IQ C|A|R|E|S One-Sheet (PDF) pantherprogram.org — Full AID Device Comparison Chart Diabetes Education Services — Tandem Turns Up the Tech: Control-IQ+ Updates tandemdiabetes.com — CGM Sensor Compatibility Reference
⚠️ This content is compiled from publicly available sources for educational purposes only. It is not medical advice. Device capabilities, software features, CGM compatibility, and clinical recommendations may change. Always consult your healthcare provider before making changes to your diabetes management. Full disclaimer.

Juicebox Podcast · juiceboxpodcast.com · Tandem Diabetes Care is a current Juicebox Podcast sponsor. Research compiled from manufacturer documentation, PANTHER Program, clinical literature & community experience.

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